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Learning Memory Cognitive
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Anti-fatigue class
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Rat tail light pain tester
The light thermal tail flick method, also known as the light thermal tail flick method or the radiation thermal tail flick method, is based on the principle of irradiating a beam of light onto the tail of a mouse to generate a heat harvesting effect, causing local warming of the tail and causing pain. When the pain threshold that the animal can tolerate is exceeded, the animal produces effective tail flick avoidance. This method is used to determine the level and changes of the animal's pain threshold, which is called the light thermal tail flick method.
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Channel type rat foot support force measuring instrument
Measuring the difference in the support force between the hind paws of rats and mice is currently an advanced method for screening analgesic and anti-inflammatory drugs. Animals will have the strength to support their body weight between the inflammatory and painful feet and the normal feet without restraint. Difference, the greater the difference, the more painful the inflammatory foot, the use of drugs with analgesic effect can reduce the difference, so as to identify the efficacy and role of anti-inflammatory and analgesic drugs.
Electronic Pain Meter
The electronic tenderness instrument is a replacement product of the XZC-A type (balance type) tenderness instrument. It has the functions of accurate pressure, convenient operation, data printing, computer connection, etc. It is one of the most practical instruments for scientific research and teaching, and has been well received by experts and professors in practical use.
Small animal thrombus generator
The instrument uses a physical method (direct current stimulation) to damage the endothelial cells of the carotid artery, thereby activating coagulation factors, starting the coagulation mechanism, causing platelets and fibrin to aggregate, and forming a mixed thrombus, which is similar to the beginning of the human body. Thrombosis, the pathological mechanism of thrombus formation by this method is very similar to that of human beings, and has more practical significance than chemical method (ferric chloride method), hematoporphyrin method, isolated circulation method, and cardiopulmonary bypass silk thread method. Therefore, electrical stimulation The tethering method has been recognized by the world.
Drinking water electric shock experiment system
The ZS-D3000 drinking water electric shock experimental system is a classic animal drinking water electric shock conflict anxiety research experiment. It can detect the efficacy of anti-anxiety drugs and reduce animal resistance behavior through punishment. A large number (up to 64 simultaneous) measurement positions can be detected. The software controls the drinking/shock ratio, shock frequency length, measurement mode, interval recording and overall duration. The number of electric shocks for drinking water in a unit time interval can be automatically transferred to an Excel worksheet.
Animal awake self-administration system
Self-administration experiment (SA) is a common method in behavioral pharmacology research. It uses the positive reinforcement effect of certain drugs to make animals establish a connection between behavior and reward through certain conditional control, thereby simulating human beings. Some cases of drug abuse.
CPP Conditioned Place Preference Video Analysis System
The CPP Conditioned Place Preference (CPP) test is a classic experimental model for evaluating drug-psychotic dependence, and it is also an effective tool widely used to find anti-drug-seeking behaviors. In this experiment, experimental animals (rats, mice) were placed in the white observation area of the conditioned place preference box, and a psychotropic drug (such as morphine) was administered, and then the experimental animals were observed in the black area and white area of the conditioned place preference box. There are small gates between the white area, the black area and the gray area for animals to shuttle freely. Each time the animals are in the dosing area, they will have a positional preference for the black and white areas under the effect of the drug's rewarding effect, and the degree of which is related to the mental dependence of the drug.
Black and white box / light and dark box experimental system
The origin of animal behavior, psychopharmacology, and behavioral toxicology are studied using animal dark-avoidance properties (black box) and exploratory properties (white box). Rodents have an innate tendency to dislike brightly lit areas and to explore new environments spontaneously, making black-and-white boxes an easy-to-use test instrument that requires no prior training of the animals. Black-and-white box tests help predict the effects of anxiolytics or anxiolytics on behavior in mice or rats. Anxious animals have been shown to rapidly shift to the darker side and rarely leave the dark side compared to animals without the anxiety trait. Therefore, more time on the bright side means less anxiety. It is widely used in learning and memory, Alzheimer's disease, hippocampal/external hippocampal research, intelligence and aging, new drug development/screening/evaluation, pharmacology, toxicology, preventive medicine, neurobiology, animal psychology and behavioral biology, etc. The fields of scientific research and computer-aided teaching in the discipline have been widely recognized in the world, and it is the first-choice classic experiment for medical schools to conduct behavioral research, especially learning and memory research.
Multifunctional cough and asthma inducer
The multi-functional cough and asthma inducer converts liquid drugs or inhalation anesthetics into mist aerosols and enters the animal's body through the animal's respiratory system under the premise of timing, quantification, and concentration and maintaining the original properties of the substance. , so that small animals have symptoms such as asthma, cough, anesthesia, etc., in order to study the prevention and treatment of such symptoms or the use of instruments for such symptoms. The instrument is a multi-purpose experimental instrument. In addition to the pharmacological cough and asthma induction experiments, it can also be used for small animals anesthesia, poisoning and drug efficacy detection of drug spray forms and to simulate high humidity environments. An instrument for both teaching and research.
Sugar water preference experimental system for rats and mice
Sugar water preference experiment, also known as Two Bottle Choice experiment, is a Ethology experimental method to study drug addiction (oral alcohol) and depressive behavior. Rodents naturally have a preference for sweetness, and when mice exhibit depressive behavior, their preference for sugar water also decreases. Lack of pleasure is an important characteristic of mental illness and behavioral disorders. This is also what most depression patients describe as' the world is gray, I can't feel what happiness is'! Based on this principle, the sugar preference experiment was used to evaluate the depressive behavior of animals and the effect of antidepressants. The sugar water preference experimental system indirectly reflects the water consumption of experimental animals by recording their licking behavior. The software can continuously sample and record the water consumption of animals 24 hours a day, and can perform statistical analysis of water consumption in different time periods.
Mouse Rotor Fatigue
The mouse rotarod fatigue instrument is improved and completed according to the similar foreign products and the rotarod test device of "Pharmacological Experiment Methodology". It has good practicability and is an ideal instrument for the screening and identification of anti-fatigue drugs.
Small animal running wheel system
Running wheels, treadmills and swimming pools are the three major sports equipment for small animal behavior, exercise physiology and pharmacology research. They have stable functions and good repeatability; they can effectively quantitatively measure animal movements; less stimulation and distraction.