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Toe volume meter
Toe volume measuring instrument is an instrument used for screening and identification of antipyretic and anti-inflammatory drugs. It is a method to evaluate the potency of drugs by measuring the swelling process of rat toes after inflammation and swelling, and to understand the action time and efficacy of drugs. regular instrument. The instrument has the advantages of accurate measurement, accurate timing, accurate printing accuracy and convenience in operation. Compared with similar foreign products, the instrument has improved a grade in terms of style, structure and accuracy, but the use of medium (liquid) Requirements and technical requirements for operation are far lower than similar foreign products.
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hot stinger
ZS-RCT-200 heat stinger is another successful product independently developed after summarizing the advantages and disadvantages of similar products at home and abroad. Have independent intellectual property rights. It adopts new methods and new technologies such as fast approach, slow stab, automatic recording, data storage and printing, PC online, etc., which makes complex and difficult experiments (such as: inverted feet, inaccurate positioning) convenient. , simple and fast. The stimulation site is precise and consistent, which ensures the real effect of the experiment. The mouse box part of the instrument is an assembly structure, which is easy to disassemble, reasonable in structure, easy to clean, and elegant at the same time.
Thermal runaway tester
The thermal escape tester can adjust the temperature arbitrarily between 2°C and 66°C, and can also set the temperature range, from low to high or from high to low. As a result, researchers can use it for pain sensitivity tests, to study the cold sensitivity of receptors, or for "dynamic" experiments under temperature changes within a certain temperature range. The real-time temperature is displayed on the LCD screen, the minimum change range is 0.1°C, and the response time is 0.1s.
Rat tail light pain meter
The light tail flicking method is also called the photothermal tail flicking method or the radiant thermal tail flicking method. When the animal produces an effective tail flick to escape, this method to judge the level and change of the animal's pain threshold is called the light tail flick method.
Channel type rat foot support force measuring instrument
Measuring the difference in the support force between the hind paws of rats and mice is currently an advanced method for screening analgesic and anti-inflammatory drugs. Animals will have the strength to support their body weight between the inflammatory and painful feet and the normal feet without restraint. Difference, the greater the difference, the more painful the inflammatory foot, the use of drugs with analgesic effect can reduce the difference, so as to identify the efficacy and role of anti-inflammatory and analgesic drugs.
Electronic Pain Meter
The electronic tenderness instrument is a replacement product of the XZC-A type (balance type) tenderness instrument. It has the functions of accurate pressure, convenient operation, data printing, computer connection, etc. It is one of the most practical instruments for scientific research and teaching, and has been well received by experts and professors in practical use.
Small animal thrombus generator
The instrument uses a physical method (direct current stimulation) to damage the endothelial cells of the carotid artery, thereby activating coagulation factors, starting the coagulation mechanism, causing platelets and fibrin to aggregate, and forming a mixed thrombus, which is similar to the beginning of the human body. Thrombosis, the pathological mechanism of thrombus formation by this method is very similar to that of human beings, and has more practical significance than chemical method (ferric chloride method), hematoporphyrin method, isolated circulation method, and cardiopulmonary bypass silk thread method. Therefore, electrical stimulation The tethering method has been recognized by the world.
Drinking water electric shock experiment system
The ZS-D3000 drinking water electric shock experimental system is a classic animal drinking water electric shock conflict anxiety research experiment. It can detect the efficacy of anti-anxiety drugs and reduce animal resistance behavior through punishment. A large number (up to 64 simultaneous) measurement positions can be detected. The software controls the drinking/shock ratio, shock frequency length, measurement mode, interval recording and overall duration. The number of electric shocks for drinking water in a unit time interval can be automatically transferred to an Excel worksheet.
Animal awake self-administration system
Self-administration experiment (SA) is a common method in behavioral pharmacology research. It uses the positive reinforcement effect of certain drugs to make animals establish a connection between behavior and reward through certain conditional control, thereby simulating human beings. Some cases of drug abuse.
skinner box
Skinner box is a typical instrument created by B.F. Skinner in the 1930s and designed to study operant conditioning, so it is also called operant conditioning test box. It is not only used to study the behavior of animals, but is widely used in the research of brain and behavioral science, such as stimulating or injuring certain parts of the brain, the effect of the use of certain drugs on animal behavior, and so on.
CPP Conditioned Place Preference Video Analysis System
The CPP Conditioned Place Preference (CPP) test is a classic experimental model for evaluating drug-psychotic dependence, and it is also an effective tool widely used to find anti-drug-seeking behaviors. In this experiment, experimental animals (rats, mice) were placed in the white observation area of the conditioned place preference box, and a psychotropic drug (such as morphine) was administered, and then the experimental animals were observed in the black area and white area of the conditioned place preference box. There are small gates between the white area, the black area and the gray area for animals to shuttle freely. Each time the animals are in the dosing area, they will have a positional preference for the black and white areas under the effect of the drug's rewarding effect, and the degree of which is related to the mental dependence of the drug.
Black and white box / light and dark box experimental system
The origin of animal behavior, psychopharmacology, and behavioral toxicology are studied using animal dark-avoidance properties (black box) and exploratory properties (white box). Rodents have an innate tendency to dislike brightly lit areas and to explore new environments spontaneously, making black-and-white boxes an easy-to-use test instrument that requires no prior training of the animals. Black-and-white box tests help predict the effects of anxiolytics or anxiolytics on behavior in mice or rats. Anxious animals have been shown to rapidly shift to the darker side and rarely leave the dark side compared to animals without the anxiety trait. Therefore, more time on the bright side means less anxiety. It is widely used in learning and memory, Alzheimer's disease, hippocampal/external hippocampal research, intelligence and aging, new drug development/screening/evaluation, pharmacology, toxicology, preventive medicine, neurobiology, animal psychology and behavioral biology, etc. The fields of scientific research and computer-aided teaching in the discipline have been widely recognized in the world, and it is the first-choice classic experiment for medical schools to conduct behavioral research, especially learning and memory research.