Language
- 中文版
- ENGLISH

Stereotaxic apparatus for large animal brain

Description Parameters Resources

Currently used stereotaxic instruments can be divided into two categories:
1. Rectilinear or Triplanar. It is composed of three imaginary three planes perpendicular to each other to form the space three-dimensional rectangular coordinates. A tiny structure deep in the brain can be located according to this coordinate system. When in use, the three-dimensional coordinate value of the electrode tip can be read out from the scale on the electrode moving frame.
2. Equatorial. It is composed of two arc beams at right angles to each other. It is made according to the principle of three-dimensional coordinates (Polar Coordinate). It can also specify the spatial position of its brain structure. It is now mostly used in human locators. This article focuses on the linear stereotaxic instrument. The basic design principles of stereotaxic are as follows.
3. Using some anatomical landmarks on the surface of animal skulls, such as the sagittal suture, the central axis of the external auditory canal, the central part of the infraorbital rim, the center of the anterior chimney (Bregma), the tip of the herringbone suture (Lamda) and the root of the upper incisors, etc. Relatively constant relationship between superficial and deep structures (such as nucleus, anterior commissure, etc.), whereby the positions of structures deep in the brain can be determined from the outside.
4. Use three-dimensional space rectangular coordinates, in millimeters, to describe the spatial location of the deep brain structures.
5. Use a sturdy metal main frame, plus several rods, clips, and head clips with accurate composition and symmetrical two sides, and press the animal's head to certain parts as fixing points, and fix it firmly (1/ 5 mm movement).
6. Use a set of electrode moving frames with three-dimensional sliding rulers that can read 1/10 mm (the lower ends of the upper and lower sliding rulers are equipped with electrode clips) to guide the electrodes, so that the electrodes can be accurately inserted into a specified structure in the brain .
7. The electrode moving frame and the metal frame for fixing the animal head are preferably two parts, and the electrode moving frame can be accurately and firmly mounted on the metal frame during use.

1. There are a variety of animal head clips (one standard, if you need to buy separately), which can be used for a variety of experimental animals. For example, some larger animals such as pigs, dogs, cats, etc., the sliding scale of the electrode moving frame can move longer.
2. The number of parts is small, the main frame is thicker, and the main parts are made of the same metal, so that the expansion coefficient of each part can be the same, and the contact potential can be avoided. The electrode moving frame and the animal head fixing clip are mounted on the main frame.
3. The electrode moving frame is easy to assemble and disassemble. When the animal head and surgical operations are performed, the electrode moving frame can be removed, and the instrument becomes a head holder that can be used independently. This ensures that the electrode moving frame is not easily damaged or distorted.
4. The instrument is equipped with multiple fully symmetrical electrode moving racks, which can insert electrodes into the brain structures with the same name on both sides at the same time, or insert multiple electrodes on the same side.
5. The vertical sliding scale of the electrode moving frame should be able to rotate a certain angle forward, backward and left and right, so that it can be used in the horizontal line of the fixed animal head, or the electrode can be inserted into the brain at a certain angle.
6. The electrode fixing clip on the electrode moving frame is required to be flexible and easy to disassemble. When used as a buried electrode, the electrode can be easily loosened and disengaged.
7. The reading of each slide rule should be able to read 1/10 mm more accurately.
8. Weight: about 10kg
9. Track length: 400mm
10. Track spacing: adjustable
11. Accuracy: ±0.1mm
12. Material: alloy material
13. Dimensions: 950×450×500mm (general size needs to be provided by the user)
14. The operating arm rotates 360 degrees, and the swing range is 180 (±90°)
15. Counting accuracy: ±0.1mm
16. Three-dimensional thruster accuracy: ±0.1mm
17. Three-dimensional advancing stroke: 80mm (X-axis: 80mm, Y-axis 80mm, Z-axis 80mm)
18. Scale laser engraving

Some published articles

1.Dexmedetomidine and Netrin-1Combination Therapy Inhibits Endoplasmic Reticulum Stress by Regulating the ERK5/MEF2A Pathway to Attenuate Cerebral Ischemia Injury

2. Transcriptome sequencing in a 6-hydroxydopamine rat model of Parkinson’s disease

3.miR-183-5p alleviates early injury after intracerebral hemorrhage by inhibiting heme oxygenase-1 expression

4.Mechanisms responsible for the effect of median nerve electrical stimulation on traumatic brain injuryinduced coma:orexin-A-mediated N-methyl-Daspartate receptor subunit NR1 upregulation

5. Intervention of Kidney - Tonifying and Essence - Filling Method on Insulin Signaling Pathway in Hippocampus of Alzheimer's Mice with Kidney Deficiency

For more literature, please consult: 400-016-4066
This parameter is the basic parameter of the equipment, please contact our company for specific parameters

Document download