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Hot and cold plate pain meter

At present, the screening test methods (physical methods) for acute pain analgesics are basically hot plate test, tail flick test or animal plantar tenderness irradiation test, but these are the normal stimulation response thresholds of animals, which belong to a kind of physiological pain. Physiological pain is essentially different from pathological pain. Physiological pain is an alarm system for self-protection for survival, while pathological pain is a disease that hinders survival. Due to the different manifestations and mechanisms of the two types of pain, their experimental methods for analgesic drugs are also different. For example, some analgesic drugs have better analgesic effects on physiological and pathological pain. However, some drugs only have an effect on physiological pain, so different experimental methods and instruments can be used to screen out drugs with different points of action. The hot and cold plate pain measuring instrument is an instrument that can complete the physiological pain experiment and the pathological pain experiment on the same instrument.

Pre-consultation

Description Parameters Resources

When the temperature of the plate surface of the hot and cold plate pain measuring instrument was set to 4°C, the test drugs could obviously change the time and times of foot-lifting on the cold plate for the animals that caused the sciatic nerve pathological pain model. When the temperature is set to 55°C, the physiological pain threshold of the animals can be accurately measured to determine the analgesic type and effect of the tested drugs. The advantage of this experimental method is that the animals are tested in an unrestrained state, which avoids human interference and damage to the animals. favorite.

In addition to the basic requirements of wide temperature setting (0°C~65°C), high temperature control accuracy (±0.1°C), and small timing error (error of 0.01 seconds), the instrument also has a Chinese LCD display and its own printer output. , External storage of USB data, complete data display, convenient observation of animals, automatic accumulation of foot lift time and foot lift times, etc. It is a truly dual-purpose analgesic drug experimental instrument.

1. Temperature setting: 0℃~60℃
2. Temperature fluctuation: ≤±0.2℃
3. Timing error: 0.01 seconds
4. Time from 25°C to 4°C: <6 minutes;
5. Time from 25°C to 55°C: <3 minutes;
6. Cold plate area: 170mm in diameter
7. Observation box size: diameter 170mm, height 220mm
8. 5-inch LCD touch screen display in Chinese
9. Internal clock
10. Foot switch trigger
11. Import data into U disk with USB port
12. Ambient humidity: 20%RH～80%RH
13. Power supply: 110V~AC220V±10% 50Hz
14. Input power: 180W
15. With foot switch
16. Ambient temperature: 10℃～28℃
17. Power supply: AC220V±10% 50Hz
18. Input power: 180W
19. Weight of the whole machine: 12kg
20. Overall size: 280*300*200mm (excluding observation box)

Some published articles

1.Exploring the biological mechanism of qi deficiency syndrome with chronic obstructive pulmonary disease (COPD) based on integrated

pharmacology

2.Study on the method of Mice Model of Qi Deficiency Syndrome induced by sleep deprivation

3.Comparison of Three Types of Diarrhea Predominant IBS Rat Model with Pi-Shen Yang Deficiency Syndrome

For more literature, please consult: 400-016-4066

This parameter is the basic parameter of the equipment, please contact our company for specific parameters

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