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shock reflex system

The Startle Reflex experiment consists of a set of sudden, relatively intense stimuli, in which animals naturally produce simple behavioral responses to external stimuli, including a series of rapid movements starting with the head and tail: Enhanced, the animal's major muscle groups appear to contract and relax. This is a sensitive indicator for evaluating animal reactivity. The shock reflex test is widely used in the study of drug toxicity, physiological auditory system, neural and behavioral genetics. Rodent studies are both convenient and effective in studying drug efficacy or evaluating the neurobiological mechanisms of shock plasticity. For example, anti-anxiety drugs reduce the shock response and reduce its magnitude, whereas anxiolytics do the opposite. Labmaze shock reflex experiment system adopts advanced three-axis acceleration digital sensor and computer network transmission technology, flexibly controls sound, light, electricity, touch and other stimuli, effectively captures the shock response of animals, can automatically complete the entire experimental process, and can analyze and record at the same time Shock reflex behavior in 16 animals. The system has high precision and convenient installation, which can effectively improve the experimental efficiency.

Pre-consultation

Description Parameters Resources

The shock reflex test is widely used in the study of drug toxicity, physiological auditory system, neural and behavioral genetics. Rodent studies are both convenient and effective in studying drug efficacy or evaluating the neurobiological mechanisms of shock plasticity. For example, anti-anxiety drugs reduce the shock response and reduce its magnitude, whereas anxiolytics do the opposite.

Labmaze shock reflex experiment system adopts advanced three-axis acceleration digital sensor and computer network transmission technology, flexibly controls sound, light, electricity, touch and other stimuli, effectively captures the shock response of animals, can automatically complete the entire experimental process, and can analyze and record at the same time Shock reflex behavior in 16 animals. The system has high precision and convenient installation, which can effectively improve the experimental efficiency.

technical parameter

1. The system can simultaneously record and analyze the shock behavior of up to 16 animals

2. The system can support sound, light, electricity, gas and other controllable methods as stimulation signals, and can realize two methods of conditioned stimulation (CS) and unconditioned stimulation (US), sound, light, electricity, tactile stimulation simultaneously or Serial occurrence, can be combined at will, can complete various typical experiments such as Habituation, Pre-pulse Inhibition (PPI), Potentiated Startle, etc., and can complete researcher's custom experiments

3. The test scheme is designed with a very user-friendly visual graphical interface, which is simple and intuitive, and what you see is what you get. You can complete the creation and modification of the experiment by clicking on the icon or frame, and the experimental mode shows a vivid image;

4. Using a three-axis digital acceleration sensor, it can fully sense the muscle group contraction response of animals in any direction, effectively solving the problem that existing equipment at home and abroad can only sense the animal's unidirectional response and electromagnetic interference.

5. Using the Ethernet data transmission technology, the experimental equipment and the computer are only connected by a network cable, and the installation of the equipment can be completed without opening the box and inserting the card, and effectively solve the problem of signal interference.

6. By choosing different sizes of restraint cages, shock experiments of animals of different weights from mice to rats can be realized

7. The analysis indicators are rich and comprehensive, including baseline mean, sampling period mean, maximum peak value, maximum peak latency period, etc., and the data can be automatically classified and counted according to the test type

8. All shock waveforms can be overlapped and displayed on the same screen, and data can be re-analyzed in a visual way

9. Analysis data can be exported to Excel, which is convenient for users to conduct in-depth data analysis

System metrics

1. Stimulation type: sound and light stimulation are the basic configuration; electrical stimulation and tactile stimulation are optional configurations

2. Acoustic stimulation:

Background white noise: it can be continuously emitted during the whole process of the experiment, and the intensity can be set by the software;

White noise stimulus: as a shock stimulus, the duration is 1-10000ms, the maximum is 126db, and the intensity can be set by software;

Pure tone stimulation: as shock stimulation, the duration is 1~10000ms, the audio frequency range is 31~16000Hz, the maximum volume is 130db, and the intensity can be set by software

3. Sensor: three-axis digital sensor, high sensitivity and strong anti-interference

4. Data transmission: The experimental box and the computer are connected through 10M/100M Ethernet

5. Number of experimental boxes: 1 to 16 experimental boxes can be connected to one computer

6. Acquisition frequency: 1000Hz, 1ms acquisition once

7. Analysis indicators: baseline mean, sampling period mean, response latency, response period mean, response period duration, maximum peak, maximum peak latency

Some published articles

1.Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain

2. The Gut Microbiota Changed by Short-term Low-dose Ethanol Withdrawal and Related to the Anxiety Like Behavior in Male Rats

3. The Effects of 4-Methylethcathinone on Conditioned Place Preference, Locomotor Sensitization, and Anxiety-Like Behavior: A Comparison with Methamphetamine

For more literature, please consult: 400-016-4066

This parameter is the basic parameter of the equipment, please contact our company for specific parameters

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